Vray Next - Substance Painter
Substance Painter 2020.1 (6.1.0) ships with VrayMtl shaders for both metallic and specular workflows. You can setup your Substance Painter project using the VrayMtl template, which will configure your viewport shader.
Under the Shader Settings, you can configure the Vray shader for working with VrayMtl.
To export textures for rendering in Vray Next, choose the Vray Mtl Output template.
Vray Material (Vray Next - Metallic/Roughness)
Vray Material (Vray Next - Specular/Glossiness
This example show the Substance Painter viewport using the Vray Metallic/Roughness shader and the Vray render using Maya.